Document Report Card

ID: ALA1158804

Journal: J Nat Prod

Title: Lupane triterpenoids from Maytenus species.

Authors: Núñez MJ, Reyes CP, Jiménez IA, Moujir L, Bazzocchi IL.

Abstract: Five new lupane triterpenes (1-5), in addition to 24 known ones, were isolated from Maytenus cuzcoina and M. chiapensis. Their structures were elucidated on the basis of spectroscopic analysis, including homonuclear and heteronuclear correlation NMR (COSY, ROESY, HSQC, and HMBC) experiments. The compounds were assayed for antimicrobial and cytotoxic activities, with 3-epi-betulinic acid and 28,30-dihydroxy-3-oxolup-20(29)-ene showing moderate cytotoxicity.

CiteXplore: 16038541

DOI: 10.1021/np058016w