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ID: ALA1158920

Journal: J Nat Prod

Title: Tubulosine: an antitumor constituent of Pogonopus speciosus.

Authors: Ma WW, Anderson JE, McKenzie AT, Byrn SR, McLaughlin JL, Hudson MS.

Abstract: From the antitumor-bioactive sap of Pogonopus speciosus, tubulosine [1] was isolated, by activity-directed fractionation using the brine shrimp lethality test, as the major antitumor constituent. 1H-nmr assignments, obtained from HETCOR and COSY, and X-ray crystallographic results are reported for the first time. Psychotrine [2] was also isolated, and its spectral data are also reported.

CiteXplore: 1982768

DOI: 10.1021/np50070a041