Document Report Card

ID: ALA1158928

Journal: J Nat Prod

Title: Antitumor agents, 118. The isolation and characterization of bruceanic acid A, its methyl ester, and the new bruceanic acids B, C, and D, from Brucea antidysenterica.

Authors: Toyota T, Fukamiya N, Okano M, Tagahara K, Chang JJ, Lee KH.

Abstract: The known bruceanic acid A [1] and its methyl ester 2, as well as the new bruceanic acids B [3], C [4], and D [5], have been isolated from Brucea antidysenterica. The structures of 1-5 were elucidated by spectral data. Compound 1 demonstrated cytotoxicity against KB and TE671 tumor cells. Compound 5 was cytotoxic against P-388 lymphocytic leukemia cells.

CiteXplore: 2089121

DOI: 10.1021/np50072a020