Document Report Card

ID: ALA1158993

Journal: J Nat Prod

Title: Inhibition of tumor-promoter-enhanced 3H-choline incorporation into cellular phospholipids by phloroglucinol derivatives from Mallotus japonicus.

Authors: Arisawa M, Fujita A, Morita N, Okuyama T, Nishino H.

Abstract: The MeOH and CHCl3 extracts of the pericarps of Mallotus japonicus showed potential anti-tumor-promoter activity. Seven constituents of the CHCl3 extract and two derivatives from the most abundant constituent, mallotojaponin, markedly inhibited the incorporation of 3H-choline into phospholipids of C3H101/2 cells enhanced by 12-O-tetradecanoylphorbol-13-acetate (TPA), a potent tumor promoter.

CiteXplore: 1800639

DOI: 10.1021/np50077a029