Basic Information
ID: ALA1159106
Journal: Bioorg Med Chem Lett
Title: Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.
Authors: Moon HI, Kim TI, Cho HS, Kim EK.
Abstract: Four oligomeric procyanidins were isolated from the MeOH extracts of the leaves of Crataegus pinnatifida (Rosaceae). Investigation of collagenase and gelatinase inhibitory natural components afforded four oligomeric procyanidins. Of these, 2 and 3 exhibited collagenase inhibitory activity (IC(50)) at a concentration of less than 1 microM, and 3 showed gelatinases A and B inhibitory activity (IC(50)) at 0.4 and 2.3 microM, respectively.
CiteXplore: 20053563
DOI: 10.1016/j.bmcl.2009.12.059
Patent ID: ┄
Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets