Document Report Card

ID: ALA1159305

Journal: J Nat Prod

Title: Vidalenolone, a novel phenolic metabolite from the tropical red alga Vidalia sp.

Authors: Yoo HD, Ketchum SO, France D, Bair K, Gerwick WH.

Abstract: The Indonesian red alga Vidalia sp. was identified as a candidate for fractionation because its crude lipid extract showed activity in a mechanism-based anticancer assay (Fyn SH2-inhibitory activity). A chemically novel phenolic metabolite, vidalenolone, as well as two previously described and structurally simple phenols, were isolated as SH2-inactive substances. Their structures were determined by an interplay of spectroscopic methods, principally 2D NMR, and reference to literature data.

CiteXplore: 11809064

DOI: 10.1021/np010319c