Tetracyclic chromane derivatives from Rhododendron anthopogonoides.

ID: ALA1177749

Journal: J Nat Prod

Title: Tetracyclic chromane derivatives from Rhododendron anthopogonoides.

Authors: Iwata N, Kitanaka S.

Abstract: Four new chromane derivatives, anthopogochromane (1), anthopogochromene A (2), anthopogochromene B (3), and anthopogochromene C (4), and two known compounds, daurichromenic acid (5) and ilicicolinic acid B (6), have been isolated from the Chinese medicinal plant Rhododendron anthopogonoides. The S absolute configuration of the stereogenic carbons in the chromane and chromene rings of 1-4 was determined from their circular dichroism spectra. Compounds 1 and 2 inhibited compound 48/80-induced histamine release from rat peritoneal mast cells.

CiteXplore: 20586436

DOI: 10.1021/np900543r

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