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ID: ALA1268981

Journal: Bioorg Med Chem Lett

Title: 2-Methyl-3-furanyl-4H-1,2,4-triazol-3-ylthioamides: a new class of selective orexin 2 antagonists.

Authors: Micheli F, Antolini M, Di Fabio R, Pellacani A, Pozzan A.

Abstract: A new class of selective orexin 2 antagonist was identified among commercial products. Initial SAR was obtained using commercial derivatives only prior to starting ad hoc medicinal chemistry activities.

CiteXplore: 20933413

DOI: 10.1016/j.bmcl.2010.09.090