In vitro antituberculosis activities of ACH-702, a novel isothiazoloquinolone, against quinolone-susceptible and quinolone-resistant isolates.

ID: ALA1275259

Journal: Antimicrob Agents Chemother

Title: In vitro antituberculosis activities of ACH-702, a novel isothiazoloquinolone, against quinolone-susceptible and quinolone-resistant isolates.

Authors: Pucci MJ, Ackerman M, Thanassi JA, Shoen CM, Cynamon MH.

Abstract: ACH-702 is a new isothiazoloquinolone with potent in vitro and in vivo activities against important bacterial pathogens, including Staphylococcus aureus. In this study, ACH-702 was found to have promising in vitro antibacterial activity against Mycobacterium tuberculosis, with MICs of

CiteXplore: 20516287

DOI: 10.1128/aac.00287-10

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