Document Report Card

ID: ALA1275440

Journal: Antimicrob Agents Chemother

Title: In vitro activity of telavancin against resistant gram-positive bacteria.

Authors: Krause KM, Renelli M, Difuntorum S, Wu TX, Debabov DV, Benton BM.

Abstract: The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC(90), 0.5 to 1 microg/ml), streptococci (all MICs, < or =0.12 microg/ml), and VanB-type enterococci (all MICs, < or =2 microg/ml). Time-kill studies demonstrated the potent bactericidal activity of telavancin.

CiteXplore: 18443122

DOI: 10.1128/aac.01398-07