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ID: ALA1275492
Journal: Antimicrob Agents Chemother
Title: In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.
Authors: Amsler KM, Davies TA, Shang W, Jacobs MR, Bush K.
Abstract: In phase 3 clinical trials for ceftobiprole treatment of complicated skin and skin structure infections, 1,219 gram-positive and 276 gram-negative aerobic baseline pathogens were identified. Ceftobiprole inhibited all staphylococcal isolates, including methicillin-resistant strains, at MICs of =4 mug/ml. Against Enterobacteriaceae and Pseudomonas aeruginosa isolates, the potency of ceftobiprole was similar to that of cefepime.
CiteXplore: 18591277
DOI: 10.1128/aac.00336-08