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ID: ALA1275495
Journal: Antimicrob Agents Chemother
Title: Clinical isolates of Aspergillus species remain fully susceptible to voriconazole in the post-voriconazole era.
Authors: Guinea J, Recio S, Peláez T, Torres-Narbona M, Bouza E.
Abstract: We studied the activity of voriconazole against 400 clinical strains of Aspergillus from the pre-voriconazole (1999 to 2002) and post-voriconazole (2003 to 2007) periods. Although the mean MICs of strains from the post-voriconazole period were slightly higher (0.39 versus 0.57 microg/ml; P < 0.001), all strains were susceptible to voriconazole and presented an MIC of CiteXplore: 18606840 DOI: 10.1128/aac.00629-08