Document Report Card

ID: ALA1275576

Journal: Antimicrob Agents Chemother

Title: In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria.

Authors: Tanaka K, Mikamo H, Nakao K, Ichiishi T, Goto T, Yamagishi Y, Watanabe K.

Abstract: The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other carbapenems. Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.

CiteXplore: 18955522

DOI: 10.1128/aac.00595-08