Document Report Card

ID: ALA1629573

Journal: Antimicrob Agents Chemother

Title: OPT-80 eliminates Clostridium difficile and is sparing of bacteroides species during treatment of C. difficile infection.

Authors: Louie TJ, Emery J, Krulicki W, Byrne B, Mah M.

Abstract: During a 10-day treatment for Clostridium difficile infection, OPT-80 and vancomycin were comparably effective in reducing C. difficile counts. Bacteroides fragilis group counts appeared unaffected with increasing dosages of OPT-80, whereas vancomycin was markedly suppressive. Retention of components of the normal microflora might lower the risk of recurrent disease.

CiteXplore: 18955523

DOI: 10.1128/aac.01443-07