Document Report Card

ID: ALA1629653

Journal: Antimicrob Agents Chemother

Title: CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids.

Authors: Zioga A, Whichard JM, Kotsakis SD, Tzouvelekis LS, Tzelepi E, Miriagou V.

Abstract: Two CMY-2 derivatives, CMY-31 (Gln(215)-->Arg) from Salmonella enterica serotype Newport and CMY-36 (Ala(77)-->Cys and Gln(193)-->Glu) from Klebsiella pneumoniae, were characterized. Both cephalosporinases functionally resembled CMY-2. bla(CMY) alleles occurred as parts of a putative transposon comprising ISEcp1B and a Citrobacter freundii-derived sequence carried by ColE1-like plasmids similar to CMY-5-encoding pTKH11 from Klebsiella oxytoca.

CiteXplore: 19104021

DOI: 10.1128/aac.01284-08