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ID: ALA1641366

Journal: Bioorg Med Chem Lett

Title: The characterization of a novel V1b antagonist lead series.

Authors: Smethurst CA, Borthwick JA, Gaines S, Watson S, Green A, Schulz MJ, Burton G, Buson AA, Arban R.

Abstract: The SAR around a V1b antagonist HTS hit 3 was explored to produce a series of thiazole sulfonamides as a lead series with selectivity over the related V1 and oxytocin receptors.

CiteXplore: 21146408

DOI: 10.1016/j.bmcl.2010.11.061