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ID: ALA1649523

Journal: Antimicrob Agents Chemother

Title: Prospective open-label study of the administration of two-percent voriconazole eye drops.

Authors: Al-Badriyeh D, Leung L, Roydhouse T, Fullinfaw R, Daniell M, Davies GE, Stewart K, Kong DC.

Abstract: Thirteen human subjects scheduled for elective anterior segment eye surgery received hourly 2% voriconazole eye drops 4 hours presurgery. No side effects were reported. Significantly, the voriconazole concentration in the aqueous humor of the eye was similar to that reported for the 1% voriconazole solution, suggestive of concentration-independent absorption.

CiteXplore: 19433565

DOI: 10.1128/aac.01700-08