5-oxo-15-HETE: total synthesis and bioactivity.

Basic Information

ID: ALA1681722

Journal: Bioorg Med Chem Lett

Title: 5-oxo-15-HETE: total synthesis and bioactivity.

Authors: Patel P, Anumolu JR, Powell WS, Rokach J.

Abstract: The first total synthesis of 6(E),8(Z),11(Z),13(E) 5-oxo-15-HETE 4 was accomplished. The synthetic material was evaluated with calcium mobilization assay and compared with 5-oxo-ETE the natural ligand for the OXE receptor.

CiteXplore: 21316960

DOI: 10.1016/j.bmcl.2011.01.032

Patent ID: ┄

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