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ID: ALA1681723
Journal: Bioorg Med Chem Lett
Title: Phellinstatin, a new inhibitor of enoyl-ACP reductase produced by the medicinal fungus Phellinus linteus.
Authors: Cho JY, Kwon YJ, Sohn MJ, Seok SJ, Kim WG.
Abstract: A new trimeric hispidin derivative, phellinstatin, was isolated from a culture broth of the medicinal fungus Phellinus linteus and its structure was established by various spectral analysis. Phellinstatin strongly inhibited Staphylococcus aureus enoyl-ACP reductase with an IC(50) of 6 μM and also showed antibacterial activity against S. aureus and MRSA.
CiteXplore: 21316961