Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors.

Basic Information

ID: ALA1759907

Journal: Bioorg Med Chem Lett

Title: Identification and optimization of tetrahydro-2H-3-benzazepin-2-ones as squalene synthase inhibitors.

Authors: Griebenow N, Flessner T, Buchmueller A, Raabe M, Bischoff H, Kolkhof P.

Abstract: Novel squalene synthase inhibitors are disclosed. SAR and pharmacological profile of selected compounds are discussed.

CiteXplore: 21396815

DOI: 10.1016/j.bmcl.2011.02.004

Patent ID: