Triamino pyrimidines and pyridines as histamine H(4) receptor modulators.

ID: ALA1770114

Journal: Bioorg Med Chem Lett

Title: Triamino pyrimidines and pyridines as histamine H(4) receptor modulators.

Authors: Meduna SP, Savall BM, Cai H, Edwards JP, Thurmond RL, McGovern PM.

Abstract: Two series of triamino pyrimidines and a series of triamino pyridines have been synthesized and their structure-activity relationships evaluated for activity at the H(4) receptor in competitive binding and functional assays. Small structural changes in these three hetereoaromatic cores influenced the functional activity of these compounds.

CiteXplore: 21458260

DOI: 10.1016/j.bmcl.2011.03.017

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