Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors.

Basic Information

ID: ALA1777787

Journal: Bioorg Med Chem Lett

Title: Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors.

Authors: Griebenow N, Buchmueller A, Kolkhof P, Schamberger J, Bischoff H.

Abstract: Novel squalene synthase inhibitors are disclosed. The design, synthesis, SAR and pharmacological profile of the compounds are discussed.

CiteXplore: 21576018

DOI: 10.1016/j.bmcl.2011.04.092

Patent ID: ┄

Associated Items: Associated Bioactivities Associated Assays Associated Compounds Associated Targets