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ID: ALA1800000
Journal: Bioorg Med Chem Lett
Title: Identification of non-amidine inhibitors of acid-sensing ion channel-3 (ASIC3).
Authors: Kuduk SD, Chang RK, Di Marco CN, Dipardo RM, Cook SP, Cato MJ, Jovanovska A, Urban MO, Leitl M, Spencer RH, Kane SA, Hartman GD, Bilodeau MT.
Abstract: A series of benzothiophene methyl amines were examined in an effort to identify non-amidine chemotypes with reduced polypharmacology from existing leads with the goal of finding potent ASIC3 channel blockers to advance the therapeutic evaluation of ASIC3 inhibition.
CiteXplore: 21669528