Document Report Card

ID: ALA1811855

Journal: J Nat Prod

Title: Xylarenones C-E from an endophytic fungus isolated from Alibertia macrophylla.

Authors: de Oliveira CM, Silva GH, Regasini LO, Flausino O, López SN, Abissi BM, Berlinck RG, Sette LD, Bonugli-Santos RC, Rodrigues A, Bolzani Vda S, Araujo AR.

Abstract: Xylarenones C-E (2-4), three new eremophilane sesquiterpenes, have been isolated from solid substrate cultures of a Camarops-like endophytic fungus isolated from Alibertia macrophylla. The structures were elucidated by analysis of spectroscopic data. Compounds were evaluated in subtilisin and pepsin protease assays, and compound 2 showed potent inhibitory activity against both proteases.

CiteXplore: 21510613

DOI: 10.1021/np1005983