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ID: ALA1828604
Journal: Bioorg Med Chem
Title: Antifungal activity of a series of 1,2-benzisothiazol-3(2H)-one derivatives.
Authors: Dou D, Alex D, Du B, Tiew KC, Aravapalli S, Mandadapu SR, Calderone R, Groutas WC.
Abstract: A series of broad-spectrum antifungal agents based on the 1,2-benzisothiazol-3(2H)-one scaffold is reported. Preliminary structure-activity relationship studies have established the importance of the presence of the heterocyclic ring, a methyl group, and a phenyl ring for optimal manifestation of antifungal activity.
CiteXplore: 21903403