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ID: ALA1914314
Journal: Bioorg Med Chem Lett
Title: Acidic triazoles as soluble guanylate cyclase stimulators.
Authors: Roberts LR, Bradley PA, Bunnage ME, England KS, Fairman D, Fobian YM, Fox DN, Gymer GE, Heasley SE, Molette J, Smith GL, Schmidt MA, Tones MA, Dack KN.
Abstract: A series of acidic triazoles with activity as soluble guanylate cyclase stimulators is described. Incorporation of the CF(3) triazole improved the overall physicochemical and drug-like properties of the molecule and is exemplified by compound 25.
CiteXplore: 21924901