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ID: ALA1926535
Journal: Bioorg Med Chem
Title: Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors.
Authors: Mathew B, Srivastava S, Ross LJ, Suling WJ, White EL, Woolhiser LK, Lenaerts AJ, Reynolds RC.
Abstract: A series of pyridopyrazine and pyrimidothiazine derivatives have been synthesized and their activity against FtsZ from Mycobacterium tuberculosis (Mtb) and in vitro antibacterial activity against Mtb H(37)Ra and Mtb H(37)Rv are reported. Certain analogs described herein showed moderate to good inhibitory activity.
CiteXplore: 22024272