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ID: ALA1955751
Journal: Bioorg Med Chem Lett
Title: Structure-activity relationship of the 7-hydroxy benzimidazole analogs as glycogen synthase kinase 3β inhibitor.
Authors: Lee SC, Shin D, Cho JM, Ro S, Suh YG.
Abstract: Design, synthesis and the GSK3β inhibitory activities of the 7-hydroxy benzimidazole analogs are described. The solid-phase synthetic route was also developed for preparation of the analogs consisting of the novel ATP competitive scaffold. In addition, the structure-activity relationship of the 7-hydroxy benzimidazole analogs and their biological activities are reported.
CiteXplore: 22325951