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ID: ALA1955765

Journal: Bioorg Med Chem Lett

Title: Wake-promoting agents: search for next generation modafinil: part II.

Authors: Dunn D, Hostetler G, Iqbal M, Messina-McLaughlin P, Reiboldt A, Lin YG, Gruner J, Bacon ER, Ator MA, Chatterjee S.

Abstract: In search of a next generation molecule to modafinil, a novel wake promoting agent, we previously disclosed bi-phenyl derived racemate compound (±)-2 as a new generation of wake-promoting agent. Here we describe the profiles of the individual enantiomers (-)-2 and (+)-2, respectively.

CiteXplore: 22341942

DOI: 10.1016/j.bmcl.2012.01.064