Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1).

Basic Information

ID: ALA1955783

Journal: Bioorg Med Chem Lett

Title: Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1).

Authors: Harikrishnan LS, Srivastava N, Kayser LE, Nirschl DS, Kumaragurubaran K, Roy A, Gupta A, Karmakar S, Karatt T, Mathur A, Burford NT, Chen J, Kong Y, Cvijic M, Cooper CB, Poss MA, Trainor GL, Wong TW.

Abstract: Identification, synthesis and structure-activity relationship of small-molecule VIPR1 antagonists encompassing two chemical series are described.

CiteXplore: 22365758

DOI: 10.1016/j.bmcl.2012.01.082

Patent ID: