Document Report Card

ID: ALA2034837

Journal: ACS Med Chem Lett

Title: Discovery of Natural Phenols as G Protein-Coupled Receptor-35 (GPR35) Agonists.

Authors: Deng H, Hu H, Ling S, Ferrie AM, Fang Y.

Abstract: We report the discovery and characterization of natural phenols as G protein-coupled receptor-35 (GPR35) agonists. Pharmacological characterization using label-free dynamic mass redistribution and Tango β-arrestin translocation assays revealed that GPR35-active natural phenols are divergent in their biased agonism.

CiteXplore: 24900447

DOI: 10.1021/ml2003058