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ID: ALA2086359

Journal: Eur J Med Chem

Title: Tormentic acid derivatives: synthesis and apoptotic activity.

Authors: Csuk R, Siewert B, Dressel C, Schäfer R.

Abstract: Several derivatives of tormentic acid have been prepared and tested for their antitumor activity. The dichloroacetate 14 is an excellent antitumor active agent acting by an apoptose inducing pathway as demonstrated by OA/PI staining, DNA laddering experiments as well as by an annexin V binding assay.

CiteXplore: 22995818

DOI: 10.1016/j.ejmech.2012.08.032