Document Report Card

Basic Information

ID: ALA2151008

Journal: Bioorg Med Chem Lett

Title: Enhanced ROS production and cell death through combined photo- and sono-activation of conventional photosensitising drugs.

Authors: McCaughan B, Rouanet C, Fowley C, Nomikou N, McHale AP, McCarron PA, Callan JF.

Abstract: A combination of light and ultrasound activation of two conventional photosensitising drugs, methylene blue and rose bengal, was shown to generate higher levels of reactive oxygen species (ROS) and lower LD50 values than either light or ultrasound activation alone.

CiteXplore: 21875807

DOI: 10.1016/j.bmcl.2011.08.015