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ID: ALA2203194

Journal: J Nat Prod

Title: Phenolic compounds from Caesalpinia sappan heartwood and their anti-inflammatory activity.

Authors: Cuong TD, Hung TM, Kim JC, Kim EH, Woo MH, Choi JS, Lee JH, Min BS.

Abstract: Four new phenolic compounds, caesalpiniaphenols A-D (1-4), together with eight known compounds were isolated from Caesalpinia sappan heartwood. The chemical structures were established mainly by NMR, MS, ECD, and Mosher's method. Compounds 4, 5, and 7 showed weak inhibitory activity against the LPS-induced NO production in macrophage RAW264.7 cells with IC(50) values of 12.2, 3.5, and 5.7 μM, respectively.

CiteXplore: 23234407

DOI: 10.1021/np3003673