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ID: ALA2375269

Journal: Eur J Med Chem

Title: Triazolothiadiazoles and triazolothiadiazines--biologically attractive scaffolds.

Authors: Khan I, Ibrar A, Abbas N.

Abstract: Contemporary medicinal chemistry faces diverse challenges from several directions, including the need for both potency and specificity of any therapeutic agent. Therefore, in the present perspective, the triazolothiadiazoles and triazolothiadiazines with broad spectrum biological profile have matured into indispensable heterocyclic scaffolds. This review article is an effort to summarize medicinal chemistry investigations over the last decade, in search for new N-bridged heterocycles which can be a rich source of promising biological activities.

CiteXplore: 23603045

DOI: 10.1016/j.ejmech.2013.01.060