Document Report Card
Basic Information
ID: ALA2390895
Journal: Bioorg Med Chem Lett
Title: Design, synthesis and structure activity relationships of spirocyclic compounds as potent CCR1 antagonists.
Authors: Hossain N, Ivanova S, Bergare J, Mensonides-Harsema M, Cooper ME.
Abstract: A series of CCR1 antagonists based upon spirocyclic compounds 1b and 2b were synthesised in which substituted aniline moiety was replaced with substituted benzamides. In vitro data revealed that CCR1 potency could be retained in such compounds.
CiteXplore: 23659855