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ID: ALA2401662

Journal: Bioorg Med Chem

Title: The synthesis of neurotensin antagonist SR 48692 for prostate cancer research.

Authors: Baxendale IR, Cheung S, Kitching MO, Ley SV, Shearman JW.

Abstract: An improved synthesis of the molecule SR 48692 is presented and its use as a neurotensin antagonist biological probe for use in cancer research is described. The preparation includes an number of enhanced chemical conversions and strategies to overcome some of the limiting synthetic transformations in the original chemical route.

CiteXplore: 23721919

DOI: 10.1016/j.bmc.2013.04.075