Document Report Card

ID: ALA3044542

Journal: J Agric Food Chem

Title: Molecular design of dinotefuran with unique insecticidal properties.

Authors: Wakita T.

Abstract: Dinotefuran, (RS)-1-methyl-2-nitro-3-(tetrahydro-3-furylmethyl)guanidine, is a neonicotinoid insecticide developed by Mitsui Chemicals Agro. Dinotefuran provides a tetrahydrofuran (THF) moiety distinct from other neonicotinoids with a chloropyridine or chlorothiazole ring, which is considered to be an essential structural element for the neonicotinoid action. The molecular design strategy based on acetylcholine ester moiety as a lead structure has successfully led to the discovery of dinotefuran with the cyclic ether THF functional group. The unique chemical and excellent biological properties and favorable toxicological profile make dinotefuran available for pest management in wide range of crops with a variety of application methods.

CiteXplore: 20919736

DOI: 10.1021/jf1030778