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ID: ALA3045160
Journal: Bioorg Med Chem Lett
Title: Betuligenol derivative with growth inhibition and antifeedant activity.
Authors: Chattopadhyay SK, Srivastava S, Sashidhara KV, Tripathi AK, Bhattacharya AK, Negi AS.
Abstract: The title chiral amine, 3-(4-methoxyphenyl)-1-methylpropylamine 5 has been synthesized from naturally abundant betuligenol 1 in three steps and also in good yield. Furthermore, the versatile intermediate 3 could be manipulated for the preparation of chiral disulphide 7. The amine derivative 5 prepared from (-)-betuligenol showed significant growth inhibition and antifeedant activity.
CiteXplore: 15026059