Naphthalenones from a Perenniporia sp. inhabiting the larva of a phytophagous weevil, Euops chinesis.

Basic Information

ID: ALA3045540

Journal: J Nat Prod

Title: Naphthalenones from a Perenniporia sp. inhabiting the larva of a phytophagous weevil, Euops chinesis.

Authors: Feng Y, Wang L, Niu S, Li L, Si Y, Liu X, Che Y.

Abstract: The new naphthalenone derivatives perenniporides A-D (1-4) were isolated from solid cultures of a fungus Perenniporia sp. inhabiting the larva of Euops chinesis, a phytophagous weevil with high host specificity to the medicinal plant Fallopia japonica. The structures of 1-4 were elucidated primarily by NMR experiments, and 1 was confirmed by X-ray crystallography. The absolute configuration of 1 and 2 was assigned by electronic circular dichroism (ECD) calculations, whereas that of the C-10 tertiary alcohol in 3 was deduced via the CD data of the in situ formed [Rh(2)(OCOCF(3))(4)] complex and supported by the ECD data. Compound 1 showed antifungal activity against five plant pathogens.

CiteXplore: 22731892

DOI: 10.1021/np300263u

Patent ID: