Rational herbicide design by inhibition of tryptophan biosynthesis.

ID: ALA3045570

Journal: Bioorg Med Chem Lett

Title: Rational herbicide design by inhibition of tryptophan biosynthesis.

Authors: Finn J, Langevine C, Birk I, Birk J, Nickerson K, Rodaway S.

Abstract: Compounds designed to mimic the tryptophan synthase alpha subunit reactive intermediate were found to be potent inhibitors of the enzyme. These compounds are herbicidal and the herbicidal mode of action was demonstrated to be due to disruption of tryptophan biosynthesis.

CiteXplore: 10476857

DOI: 10.1016/s0960-894x(99)00340-6

Patent ID: ┄