Design, synthesis and structure-activity relationship of novel insecticidal dichloro-allyloxy-phenol derivatives containing substituted pyrazol-3-ols.
Basic Information
ID: ALA3045955
Journal: Pest Manag Sci
Title: Design, synthesis and structure-activity relationship of novel insecticidal dichloro-allyloxy-phenol derivatives containing substituted pyrazol-3-ols.
Authors: Li M, Liu CL, Zhang J, Wu Q, Hao SL, Song YQ.
Abstract: BACKGROUND: Pyridalyl, consisting of dicholoro-allyoxy-phenol moiety, is a novel class of insecticide showing extraordinary activities against various lepidopterous and thysanopterous pests on cotton and vegetables. To discover further novel insecticides, a series of new dichloro-allyloxy-phenol derivatives containing substituted pyrazol-3-ol moieties were designed and synthesised via the intermediate derivatisation method. RESULTS: The target compounds were characterised by (1) H NMR, IR, MS and elemental analysis. Bioassays indicated that some of these compounds exhibited good insecticidal activities against diamondback moth (Plutella xylostella) at 6.25 mg L(-1) . The structure-activity relationship is discussed. CONCLUSION: The present work demonstrates that dichloro-allyloxy-phenol derivatives with substituted phenylpyrazole moieties can be used as lead compounds to develop further novel insecticides.
CiteXplore: 23139228
DOI: 10.1002/ps.3417
Patent ID: ┄