Document Report Card

ID: ALA3046354

Journal: J Agric Food Chem

Title: Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system.

Authors: Shao X, Li Z, Qian X, Xu X.

Abstract: To replace nitromethylene pharmacophore with a nitroconjugated system, a series of novel neonicotinoid analogues bearing five-membered aromatic heterocycles were designed and synthesized. Bioassays indicated that some of the synthesized compounds exhibited higher insecticidal activities than imidacloprid against cowpea aphids ( Aphis craccivora ), armyworm ( Pseudaletia separate Walker), Nephotettix bipunctatus (Fabricius), and small brown rice planthopper ( Laodelphasx striatellus ). Exhilaratingly, the activity levels of derivatives 13a and 13j rivaled that of imidacloprid.

CiteXplore: 19138119

DOI: 10.1021/jf803305f