Synthesis and antimicrobial activity of (1,4-phenylene)bis(arylsulfonylpyrazoles and isoxazoles).

Basic Information

ID: ALA3112509

Journal: Eur J Med Chem

Title: Synthesis and antimicrobial activity of (1,4-phenylene)bis(arylsulfonylpyrazoles and isoxazoles).

Authors: Lavanya G, Mallikarjuna Reddy L, Padmavathi V, Padmaja A.

Abstract: A new class of (1,4-phenylene)bis(arylsufonylpyrazoles and isoxazoles) were synthesized by 1,3-dipolar cycloaddition of nitrile imines and nitrile oxides to the 1,4-bis((E)-2-(arylsulfonyl)vinyl)benzenes in the presence of chloramine-T. Compound 7f exhibited pronounced antimicrobial activity.

CiteXplore: 24398288

DOI: 10.1016/j.ejmech.2013.11.041

Patent ID: