ID: ALA3227928
Journal: J Med Chem
Title: Phosphonate analogue of 2'-deoxy-5-fluorouridylic acid.
Authors: Montgomery JA, Thomas HJ, Kisliuk RL, Gaumont Y.
Abstract: The phosphonate analogue (6) of 2'-deoxy-5-fluorouridylic acid has been prepared via a Pfitzner--Moffatt oxidation and Witting reaction. This compound was found to inhibit thymidylate synthetase from three sources and to be cytotoxic to H.Ep.-2 cells in culture.
CiteXplore: 423172
DOI: 10.1021/jm00187a024
Patent ID: ┄