A,D-seco-limonoids from the stems of Clausena emarginata.

ID: ALA3232732

Journal: J Nat Prod

Title: A,D-seco-limonoids from the stems of Clausena emarginata.

Authors: Xia HM, Li CJ, Yang JZ, Ma J, Chen XG, Zhang D, Li L, Zhang DM.

Abstract: Twelve new A,D-seco-limonoids, clauemargines A-L (1-12), and three known analogues were isolated from the stems of Clausena emarginata. The absolute configurations of 1 and 5 were confirmed by X-ray crystallography and ECD spectroscopy, respectively. Compounds 1, 2, 8-10, and 13 showed moderate inhibitory effects on LPS-induced NO production (IC50 values<10 μM).

CiteXplore: 24593150

DOI: 10.1021/np400797s

Patent ID: ┄