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ID: ALA3243981

Journal: J Med Chem

Title: Antileukemic activity of ungeremine and related compounds. Preparation of analogues of ungeremine by a practical photochemical reaction.

Authors: Zee-Cheng RK, Yan SJ, Cheng CC.

Abstract: A number of alkoxypyrrolophenanthridinium salts and their analogues related to the antileukemic alkaloid ungeremine were prepared by a practical photochemical cyclization. The importance of the quaternary nitrogen atom and of alkoxy groups, the planarity of a molecule, and steric considerations relative to antileukemic activity are discussed.

CiteXplore: 621715

DOI: 10.1021/jm00200a011