ID: ALA3244134
Journal: J Med Chem
Title: Potential anticancer agents. 16. Methotrexate analogues with a modified peptide side chain.
Authors: Suster DC, Tărnăuceanu E, Ionescu D, Dobre V, Niculescu-Duvăz I.
Abstract: Nine analogues of methotrexate, in which the side chain is modified by replacement of the terminal glutamyl moiety with other amino acids, were synthesized from 2,4-diamino-6-(chloromethyl)pteridine. None of these compounds exhibited significant activity against L1210.
CiteXplore: 722722
DOI: 10.1021/jm00209a015
Patent ID: ┄