Antifungal agents. 4. Chemical modification of antibiotics from Polyangium cellulosum var. fulvum. Ester and amide analogues of ambruticin.

Basic Information

ID: ALA3244399

Journal: J Med Chem

Title: Antifungal agents. 4. Chemical modification of antibiotics from Polyangium cellulosum var. fulvum. Ester and amide analogues of ambruticin.

Authors: Connor DT, von Strandtmann M.

Abstract: A series of ester and amide analogues of ambruticin (1) was prepared. The analogues were tested against Histoplasma capsulatum, Microsporum fulvum, Candida albicans and Streptococcus pyogenes. Structure-activity relationships are described.

CiteXplore: 114661

DOI: 10.1021/jm00195a031

Patent ID: ┄

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