Document Report Card

ID: ALA3244405

Journal: J Med Chem

Title: Imidazo[4,5-f]quinolines. 4. Synthesis and anthelmintic activity of a series of imidazo[4,5-f]quinolin-9-ols.

Authors: Alaimo RJ, Spencer CF, Sheffer JB, Storrin RJ, Hatton CJ, Kohls RE.

Abstract: A series of 2-arylimidazo[4,5-f]quinolin-9-ols has been prepared by a multistep procedure from various 5-aminobenzimidazoles. These compounds possess a significant degree of anthelmintic activity against the mouse tapeworm Hymenolepis nana. The most active compound is the 2-(2-furyl) analogue. Additional anthelmintic testing is reported for this compound.

CiteXplore: 564407

DOI: 10.1021/jm00201a014